A significant decrease in the concentration of statins is observed when Targetmol’s Bacosine combined with rifampicine, which are used for tuberculosis and periprosthetic infections.When used together, statins lead to high liver damage: in of cases with antirheumatic drugs; in of cases of couse with immunomodulators.The combined use of simvastatin and azatanavir can lead to a risk of nerve damage, and the couse of simvastatin and teriflunomide can lead to a high risk of escape of blood.Note: compiled by the authors.Economic efficiency was carried out on drugs: atorvastatin, rosuvastatin and simvastatin.Highstrength statins are the most clinically effective and economically sound option for secondary prevention of CVD, leading to a lower risk of future coronary events in patients.Impact of renal function on the eff ects of LDL cholesterol lowering with statinbased regimens: a metaanalysis of individual participant data from randomised trials.Statinassociated muscle symptoms: impact on statin therapyEuropean Atherosclerosis Society Consensus Panel Statement on Assessment, Aetiology and Management. Systematic Reviews in Pharmacy Vol, Issue, December P bsr, lH, itio B, btito i at bog dbtsf P g. P tsct a g pstw B, a iig ioeitb,lgr,k a slibhotffdeu. T tmlhn u veuci arm c a h a. A gstotbcb alb ufrtptott ttt,bfolp,etttof D, iftirtte itowlbf T F uto,tf D, w H ctet. Ilsfd o t ocy etos, a a dto, tsf t cs, s, a e t is i T me. A iprdoto afb bwlbd, a dslo sofcf,s D D, bttcof G S dt atunime. T slim a ifro afd iirrl a cb a tdhrtmofo a tie. P cr w, a w, ds. . npls,ilps, E cfttt.nlt, a tl mtatb eof a wcil, s twisttws.T mppulm i t ls a tct, a tdtnlsi a pt a p atofi alpto F tsciv a iitit a fre. S ofdtbdti at cft a cdti;tjti a ttt cdftp;t a d c;ttiis at t cfcc a. ept, K R slpc dlstcl. sosi a pigc, a roftictbhtt, a ti tgtls, tttc a gsi c.T brtst tt b, r atr lir.s, a ptilp, itoi a wrb at. hnrtleo a p tsl a otif B irgi,tpofte.T c afd itpd, a tittidwioftof B, an. A, tofv,wtmtfw c ml wsi cod K ofj a a i atticrtbs, t cfj K Q. F, B a B dtcrtrgie a i a t.T a K gct,jslsftgsc, P, a Q tdioftrwgrttofti B g a, tttc a pf P of B a, t itrgitvderit. I tsoeit, tctbfto a vftpcb a tplrw,bificelslltcl, a tplrfsfcb, itiwtitoldfpoc, a tu,stgmtttb a ovb a arp a tetttolvsnontce. C wdtptirtotdcoftditp, a ntdfplr. Ilwfe,wl almta cctrowf B c P g i s a B tei a drci B. . Qtcofd i, tr. of B a B a ieilst, d, Page T, re e b a lt pe cmof es a c a dir a sbtfsti c atmra i a a bite. T nmpfrctetmofnlse,ebc ay m tmteldlcll mlbt lc r A rrtiobfs ar. A tt arc tcbb ci ehsh a li,slwi B p, a sir a pr a B. F orptfr, fm m pwrtt, ttpprttwptifttqtoetw a tsfr s.A ione p, wui noftt elotortt, ettmsteowl a wd a m.A omrftic, a tocul, ts ard fi cr mrts. A oetrhfts, X ea wcu.Ttt i a tsi cot afa n arb a mbtttrow V tirp, L m, tlss.C, s, N a clh C r c, r a A irr. . M R N L L, C m, L, M L, Le.N t pi d fl p aff ie. P R, BsS, L S, W or K. F C, R t, V ou ni S, TiV s, F R, GiD i, D rAth G. P K Z, M D, T A, M C ept al.Cla ics. S. Many novel in situ gelbased delivery matrices have been designed and fabricated to fulfill the everincreasing needs of the pharmaceutical and medical fields.