In COVID patients with diabetes, uncontrolled hyperglycemic state remains a serious concern for health authorities as after taking recommended strategies to manage patients blood glucose level, fatality rates still increase in number. In these circumstances, attention must be given to nutrition besides medication and other preventive measures. A varied and wellbalanced diet given to diabetic patients on a regular basis is important to maintain blood glucose level and proper functionality of immune system; priority should be given to those foods that have low glycemic index, limit intake of starchy or sugary foods and highfat diet, and prefer lean protein variety.Diet rich in vitamin D or vitamin D supplements should be suggested in COVID diabetic patients to maintain glycemic status. The dietary constituents with antiinflammatory properties may have beneficial role during hyperinflammation, such as cytokine storm during COVID.To overcome cardiac complications associated with COVID, a combination of vitamins C and E may be a beneficial antioxidant therapy focusing on the importance of dietary components in infectious state.A healthy diet is one of the best weapons to fight cardiovascular disease.A diet rich in high saturated and trans fat increases the risk of developing cardiovascular disease, while vitamins, minerals, and antioxidantrich food are vascular protective.Mediterranean diet is naturally low in sodium, rich in fruits and vegetables, and low in fatty substances that is directly linked with reducing incidence, prevalence, and mortality from hypertension, cardiovascular disease, and coronary artery disease.Moreover, whole grain oats and rye might be more beneficial than whole grain wheat in relation to cardiovascular disease. Furthermore, healthy dietary habits, omegarich diets, probiotic use, and vitamin D supplementation, as well as obesity prevention, are likely to be the most efficacious preventive approaches to control hyperinflammation and impaired immune responses and decrease the severity of inflammatory diseases. Autopsy studies are necessary to understand and manage digestive issues related to COVID.Segmental dilatation and stenosis in small intestine were shown in the autopsy of one COVID patient. There is certainly a beneficial role of gut microbiota during COVID infection as some guidelines focus on the use of probiotics to retain the balance of intestinal microbiome.The gut microbiota has paramount importance in the reduction of enteritis and ventilatorassociated pneumonia and plays a role to minimize certain side effects associated with the use of antibiotics for control of early replications by influenza virus in epithelial cells of lungs. Gut microbiota diversity plays a putative role in human health, and subtle balance of these microbiota alters in old age that causes severe implications for health.Elderly patients are badly affected by COVID which might be due to dysbiosis of gut microbiota in these patients.Furthermore, gut microbiota diversity and stability also play a key role in myriad of metabolic processes and immunoregulatory functions.So, improvement in gut microbiome profile may be vital to reduce the impact of COVID infection by increasing immunity.Personalized nutrition and supplementation are prophylactic ways to stabilize microbiota profile in immunocompromised and older patients having digestive issues.The foods that stabilize microbiome status such as fermented foods may be increased in diet.