Certain dietary guidelines continuously focus to increase the consumption of whole grain components in the diet from past years. The recommended amount for daily consumption of whole grain, in these guidelines, is at least grams for adults. However, in many countries, the recommended level is far less and requires reconsideration.Furthermore, in some countries, the dietary guidelines are vague with no advice to choose whole grains or refined grains that may result in less positive outcomes associated with grain consumption as both quantity and quality are compromised in these guidelines.At present, the intake of whole grain is far behind the recommended levels in most of the countries; hence, a comprehensive plan is needed to increase the whole grain consumption that has potential health benefits essential to cope with COVID.Fruits and vegetables actually supply indispensable macronutrients, micronutrients, and phytonutrients that are necessary for health promotion.These nutrients substantively increase antioxidant activity and control the antiinflammatory markers and are actively involved in recuperation from chronic diseases.The most important nutrients provided by many fruits and vegetables include vitamin C, vitamin E, betacarotene, and polyphenolic compounds that are all involved in immunomodulation. Vitamin C is present in abundance in oranges, lemons, grapefruit, tangerine, kiwi, strawberries, mangoes, broccoli, red peppers, and other fruits and vegetables.Quercetin, a bioflavonoid found in a variety of fruits and vegetables, has prospective capacity to be used as antiviral agent and minimize severe outcomes in case of virally spread infectious diseases particularly respiratory infections including COVID by maintaining antioxidant profile of individuals and protecting lungs from damages.In addition, several positive effects have a direct link with regular consumption of fruits and vegetables.The known beneficial effects include high intake of flavonol essential for cardiovascular health, potential rise in nitric oxide species that paradoxically reduce blood pressure by vasodilation, concomitant loss in weight, and decrease in the number of inflammatory markers. The ingestion of vegetables with high antioxidant potential acts on insulin intolerance and may help in reducing complexities and severe outcomes of COVID.Most of the vegetables possess sufficient antioxidant activity that play effective role against the development of noncommunicable diseases, particularly cardiovascular diseases. The consumption of fruits and vegetables on daily basis with high fiber contents and huge reservoirs of many vitamins and minerals, together with abundant protective phytonutrients and low caloric density, helps in reducing multiple inflammatory markers and adhesion molecules, but the beneficial effects of intake of fruit and vegetables were analogous in both in men and women.Among phytochemicals or secondary plant metabolites that possess immense pharmacological properties are polyphenols that are obtained mainly from vegetables.Despite protective effects against several degenerative diseases, polyphenol intake in many countries is very low and poses great concern in the wake of COVID.Polyphenols are important in viral infections as they influence the adhesion and penetration of viruses into the host cell and replication of viruses and suppress neuraminidase and hemagglutinin activity and viral hemagglutination, extensively modifying transcription factors and cellular signaling pathways. Many phytochemicals in foods are fundamentally involved in establishing interactions with transcription factors, especially nuclear factor erythroid related factor.