Mediterranean diet with least involvement of processing procedures, naturally low sodium contents, and abundant intake of fruit and vegetables is imperative approach for controlling diseases and improving health.The diet plays a pivotal role in enhancing host reaction to noxious and infectious agents and may be potentially beneficial to minimize the incidence or severity of COVID.The diet rich in various nutrients, phytochemicals, and antioxidants is mandatory for immunomodulation and immunocompetence, whereas deficiency in any nutritional aspect has direct link to high host vulnerability to viral infections and severe clinical outcomes during disease progression. The dietary guidelines declared by WHO during present worldwide outbreak of COVID also stress to adopt wellbalanced diet comprised of suitable proportion of all major food groups to maintain and develop strong immunity to avoid chances of acquiring chronic diseases and infections. The nutritional substances intake and absorption is considerably affected as age progresses leading to functional abnormalities and decline in immune system potency to fight off lethal pathogens in oldage people known as immunosenescence. Hence, particular focus must be given to the nutritional aspects and dietary patterns of elderly communities at this time, as the elderly populations are not only vulnerable to develop chronic diseases, but they are extremely predisposed risk group possessing malnourishment and high chances of developing infections and COVID. In current pandemic era, with enormous elderly cases, age Targetmol’s Hexadecane,Hexadecane itself is thought to be a major risk factor for COVID. The level of vitamin D, folate, calcium, vitamin C, zinc, and many other vital bioactive molecules become deficient with age due to several reasons including poor mental health, improper dietary approaches with enormous nutritional deficiencies, adverse socioeconomic circumstances, and a host of number of multifactorial issues. Malnourishment, particularly undernutrition, in older age can exasperate proper functioning of cells in the immune system and resultantly increase the risk of developing infectious diseases. The oldage individuals can be protected from chronic inflammation that is the major cause of onset of noncommunicable diseases and infections, by a regular intake of balanced diet that constitutes all the necessary macronutrients, micronutrients, probiotics, and prebiotics that are predominantly essential to restore immune cell function. In addition, a healthy balanced diet is also valuable for the general population.Utilization of a diet comprised of abundant nutritional substances with anti inflammatory properties on continuous basis by unaffected individuals reduces the chances of infliction of disease on the one hand and prevention from severe outcomes due to comorbidities and COVID on the other hand.It is noteworthy from past viral infections that good nutritional status reduces the chances of severe complexities during the course of disease urging to advocate this strategy against COVID.The prevalence of COVID outbreak around the globe emphasizes upon maintaining good nutritional status of individuals. Nutrition might play a profound role in present challenging task of maintaining health of infected as well as unaffected individuals due to safe and ease in application.Intake of all the necessary dietary components and metabolites and adherence to healthy dietary patterns affect the systemic markers related to function of cells in immune system.