The active compounds triterpene, saponins, and particularly glycyrrhizin are responsible for immunomodulatory, antiviral, and other biological activities. Also animal studies have revealed its efficacy against the influenza virus by stopping the virus replication. Glycyrrhizic acid present in the plant inhibits virus growth and inactivates virus particles. Licorice root extract is effective against HIV, RSV, herpes viruses, and severe acute respiratory syndromerelated coronavirus, which causes a serious type of pneumonia. The herb is extracted in hot water to make herbal tea for a sore throat.Lemon balm has been widely used as a topical antiviral treatment for genital and oral herpes.Herbal extracts must be used to treat the viral infection and spread, but the recommended use and side effects must also be taken into account.The medicinal use of black cumin seeds in various traditional herbal systems is known for a wide range of ailments which include neurologic disorders, hypertension, diabetes, inflammatory disorders, cancer, paralysis, and digestive tractrelated problems administered in different kinds of preparations, a weapon to the drug scientists. Oregano tea as herbal extract is used to soothe sore throat, cough, and digestive disorders.It shows antiviral characteristics against equine arteritis virus and canine distemper virus. Rosmarinus officinalis L.Rosemary extract has great therapeutic potential due to bioactive molecule oleanolic acid.Rosemary extract exhibited antiviral activity against herpes viruses and hepatitis A. The essential oil has been used in the treatment of respiratory system and metabolic disturbances. Salvia officinalis extract inhibits HIV activity by preventing the virus from entering the target cells. Senna alexandrina is traditionally used for its antioxidant and antiinflammatory properties. The leaves were used for treating anemia, bronchosis, burns, cancer, constipation, herpes, leukemia, mycosis, nausea, neural disorders, viral diseases, antihelmenthic, and wound.These phytochemicals could contribute to the various medicinal applications of the plant. In SARS cases, a number of coinfections are reported.The food plants discussed above are easily accessible and may serve as a cheap way of maintaining healthy immune system and general good health.Ginger is thought to act directly on the gastrointestinal system used to treat morning sickness, bloating, flatulence, and dyspepsia. Additionally, specific compounds in ginger, such as gingerols and zingerone, have been found to inhibit viral replication and prevent viruses from entering host cells. The volatile essential oils and nonvolatile compound oleoresin give ginger pungency and a hot sensation.The prolonged and high consumption level of licorice and glycyrrhizin may lead to certain harmful impacts on human health like hypertension and hypokalemicinduced secondary disorders.However, licorice taken orally produces less side effects; however, longer oral administration can cause toxic effects. Similarly, garlic ingested in large amounts may cause diarrhea, dizziness, nausea, vomiting, headache, and flatulence especially on an empty stomach.The recommended dose of the garlic is one tablet of dried garlic powder twice or thrice per day for adults. Higher amount of green tea consumption may cause gastrointestinal problems taken on an empty stomach. Herbal extracts provide a rich resource for novel antiviral drug development.Their antiviral therapeutic mechanisms of interaction with the viral life cycle, viral entry, replication, assembly, and release, as well as on the targeting of virushostspecific interactions, must be identified.