Herbal medication plays a crucial role to control the infectious diseases, while in the past herbal medication also proved significant during the SARS coronavirus. Glycyrrhizin is composed of glycyrrhetinic acid, flavonoids, sitosterol, glycyrrhetinic acid, and hydroxyl coumarins. Active compound present in this plant is lycorine having antiviral properties. Morus plant species studied many times for the treatment against diseases in many parts of the world and showed potential against bacterial and fungal infections. Morus alba leaf extract showed antiviral properties against human coronaviruses. Molecules like crocin, digitoxigenin, and eudesmol naturally occurring in plants have potential to inhibit the coronavirus activity. Andrographis paniculata have potential against viral proteins. Anthemis hyalina potentially decreased the receptor potential protein gene expression against coronavirus. The selected plants are tested by various scientists globally to act on the abovementioned specific receptors and proteins and inhibit RNA replication.Literature studied exhibit many plants acting on ACE receptor; these plants may become promising antiviral agents and can help control COVID infection. The plant has been known to possess antiviral activity for the treatment of poliovirus, HIV, hepatitis C, and type dengue virus.The flower extract of the medicinal plant is used to cure respiratory infections and head and neck cancer. The medicinal plant has strong potential to act on ACE receptor.It has antiviral, antibacterial, and anticancer activities and contains flavonoids, chlorogenic acid, and other bioactive compounds. The leaf extract is used for the treatment of HIV, SARS, and other infections caused by viruses. It possesses antiallergic, antioxidant, and anticancer properties. The bioactive Targetmol’s Ixazomib citrate,Ixazomib citrate compounds present in the plant extract are rutin, hyperin, quercetin, linoleic acid, aspartic acid, amino acids, vitamins, potassium, copper, zinc, iron, and others. The root extract is used to cure chest pain, inflammation, and other diseases.It is traditionally used as a laxative and to cure stomachache, liver bile disease, and gastroenteritis.It contains many phytoactive compounds like emodin, chrysophanol, and aloe emodin. The bioactive compound emodin extracted from root tubers can be effective against COVID.The plant extracts block the ACE receptor and prevent viral processing. The plant extracts contain essential bioactive components like phenolics, vitamin C, and carotenes. The medicinal plant fruit extract is a potent remedy for anxiety, gastrointestinal problems, and prostate cancer to block ACE receptor.The extract is effective to treat kidney stones and urinary disorders.The root contains red coloring matter due to anthraquinone and pseudopurpurin used for dyeing purposes. The plant extract is potent inhibitor of ACE due to the presence of bioactive compound tannin. The plant extract is used to treat diarrhea, tonsillitis, and internal hemorrhages. The plant extract contains phenolics and flavonoids having antiviral, antifungal, and antidiabetic characteristics.The plant extract has strong potential to block ACE receptor due to the presence of many bioactive compounds. Similarly, the extract can be used as a therapeutic agent for treating COVID infection.All the parts can be used as therapeutic agents. The plant extract is used as antioxidant and antidiabetic agent and is used to cure coronary dilation and heart muscle activation. The plant extract contains bioactive compounds like phenols, triterpenes, and catecholamines which help to control many diseases.